Publications
Selected publications
Key peer-reviewed articles and open-access resources that underpin the laboratory's research themes. Links point to PubMed, PMC or publisher records where available.
Cancer Research
LSD1 and aberrant DNA methylation mediate persistence of enteroendocrine progenitors that support BRAF mutant colorectal cancer
Cancer Discovery
Bacterial-driven inflammation and mutant BRAF expression combine to promote murine colon tumorigenesis that is sensitive to immune checkpoint therapy
Cancer Cell
Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG islands
PLoS Genetics
Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island
Cancer Research
Mismatch repair proteins initiate epigenetic alterations during inflammation-driven tumorigenesis
Journal of Molecular Cell Biology
Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage
Cancer & Metabolism
Inflammation-induced DNA methylation of DNA polymerase gamma alters the metabolic profile of colon tumors
Proceedings of the National Academy of Sciences